Prognostic potential of neutrophil-to-lymphocyte ratio and lymphocyte nadir in stage III non-small-cell lung cancer

Title: Prognostic potential of neutrophil-to-lymphocyte ratio and lymphocyte nadir in stage III non-small-cell lung cancer
Creator: Kang, Kylie H.; Efird, Jimmy T.; Sharma, Neelesh; Yang, Michael; Dowlati, Afshin; Linden, Philip; Machtay, Mitchell; Biswas, Tithi
Relation: Future Oncology Vol. 13, Issue 16, p. 1405-1414
Publisher Link: http://dx.doi.org/10.2217/fon-2017-0045
Publisher: Future Medicine
Resource Type: journal article
Date: 2017
Description: Aim: Studies have shown increased pretreatment neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios to be predictive of survival in various cancers. Our aim was to evaluate the prognostic role of such inflammatory markers in non-small-cell lung cancer (NSCLC). Methods: One hundred and sixty-three patients with stage III NSCLC who received definitive treatment were included. Survival analysis was performed using Kaplan–Meier method. Hazard ratios for overall and recurrence-free survival were estimated using Cox proportional hazards model. Results: Both neutrophil-to-lymphocyte >Q75 (4.5) and lymphocyte nadir values
Subject: inflammatory serum markers; NSCLC; prognostic model
Identifier: http://hdl.handle.net/1959.13/1354408
Identifier: uon:31264
Identifier: ISSN:1479-6694
Language: eng
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